Illustration of the Pathways Involved in Association of Genetic Variation and Frame Effect


Illustration of the Pathways Involved in Association of Genetic Variation and Frame Effect

Abstract

Previous studies demonstrated that the various single and multiple genetic variations are associated with intermediate or behavioral phenotypes, which lead to different emotional decision-making and subsequently different susceptibility to framing effect. Researchers in many prior literatures were focused mainly on identification of the 5-HTTLPR-variation roles and processes involve in regulation of the serotonin level in brain region, which associated with behavioral traits in human. In this paper we comprehensively illustrate the identified brain regions, which might associate with framing effect. We also explain the pathways involved from gene to individual behavior and how does the specific allelic variation leads to different behavioral phenotype through effecting various brain areas activation. Discussing the previous findings highlights that the existing knowledge in this field is not efficient and complete. Thereby, we suggested that the further studies are required on other known candidate genes. Moreover we argued that the correlation of nongenetic factors with genetic variation as well as gene-gene interactions must be study in details in future to determine the effects of frame effect in different population and specifically in distinct individuals.

Authors:- Hamed Taherdoost and Saba Montazeri

Keywords: Frame Effect, Decision Making, Brain Function, Marketing Management

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